Patterns of Amino Acids near Signal-Sequence Cleavage Sites
نویسندگان
چکیده
منابع مشابه
A new method for predicting signal sequence cleavage sites.
A new method for identifying secretory signal sequences and for predicting the site of cleavage between a signal sequence and the mature exported protein is described. The predictive accuracy is estimated to be around 75-80% for both prokaryotic and eukaryotic proteins.
متن کاملPhotosensitized DNA cleavage promoted by amino acids.
A novel class of DNA cleavage agents are reported that derive activity from amino acids tethered to a photoactive intercalator.
متن کاملBLOMAP: An encoding of amino acids which improves signal peptide cleavage site prediction
Research on cleavage site prediction for signal peptides has focused mainly on the application of different classification algorithms to achieve improved prediction accuracies. This paper addresses the fundamental issue of amino acid encoding to present amino acid sequences in the most beneficial way for machine learning algorithms. A comparison of several standard encoding methods shows, that ...
متن کاملLabCaS: labeling calpain substrate cleavage sites from amino acid sequence using conditional random fields.
The calpain family of Ca(2+) -dependent cysteine proteases plays a vital role in many important biological processes which is closely related with a variety of pathological states. Activated calpains selectively cleave relevant substrates at specific cleavage sites, yielding multiple fragments that can have different functions from the intact substrate protein. Until now, our knowledge about th...
متن کاملPredicting Protein–Protein Interaction Sites Using Sequence Descriptors and Site Propensity of Neighboring Amino Acids
Information about the interface sites of Protein-Protein Interactions (PPIs) is useful for many biological research works. However, despite the advancement of experimental techniques, the identification of PPI sites still remains as a challenging task. Using a statistical learning technique, we proposed a computational tool for predicting PPI interaction sites. As an alternative to similar appr...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Journal of Biochemistry
سال: 1983
ISSN: 0014-2956,1432-1033
DOI: 10.1111/j.1432-1033.1983.tb07424.x